New CEHG Publication: Limitations of GCTA as a solution to the missing heritability problem

Biology graduate student Siddarth Krishna Kumar and his advisor Professor Shripad Tuljapurkar, with Professors Marcus Feldman (Biology) and David Rehkopf (Medicine), have shown that Genome wide Complex Trait Analysis (GCTA) does not reliably estimate the heritability of complex traits. This work was recently published in the Proceedings of the National Academy of Sciences (

A critique of this work by the GCTA authors can be found (, and a response to this critique can be found at ( )


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